Clinical Chemistry Podcast

Melissa Ix, Richard Dodel, J Alexander Ross. Alpha-Synuclein-Specific RT-QuIC As a Tool for the Differential Diagnosis of Neurodegenerative Diseases Using Peripheral Tissues. Clinical Chemistry , Volume 72, Issue 8, August 2026, Pages 830–844. https://doi.org/10.1093/clinchem/hvag037

Matthew Lee, Jeffrey A SoRelle, Arun Everest-Dass, David E Gerber, Mitchell S von Itzstein. Predictive Biomarkers for Immune Checkpoint Inhibitor Efficacy: Challenges, Innovations, and a Pathway to Precision Medicine in the Era of Cancer Immunotherapy. Clin Chem 2026; 72(9): 926–47. https://doi.org/10.1093/clinchem/hvag062

Shengjie Li, Jiazhen Cao, Jun Ren, Kun Chen, Jianing Wu, Yingzhu Li, Yunxiao Song, Chengxun Li, Wenjun Cao, Ming Guan. Tumor-Derived HAVCR1 As a Reliable Fluid Biomarker for the Diagnosis of CNS Lymphoma. Clin Chem 2026; 72(8): 880–92. https://doi.org/10.1093/clinchem/hvag036

Luuk F P Giesen, Jeroen A Roest, Frederique M A Koopman, Martine M L Deckers, Helena Chon, Christian M Hackeng, Jurgen A Riedl, Michiel de Bruin, Brooke M Katzman, Warry van Gelder, Janne Cadamuro, Mads Nybo, Michael A Fouraux, Thijs C van Holten, Robert de Jonge. Performance, Safety, and Patient Experience of an Autonomous Robotic Phlebotomy Device: A Multicenter Trial. Clinical Chemistry, Volume 72, Issue 8, August 2026, Pages 845–856. https://doi.org/10.1093/clinchem/hvag029

Ingar Ziad Restan, Yong Yong Tew, Ole-Thomas Steiro, Ziwen Li, Hilde L Tjora, Jørund Langørgen, Torbjørn Omland, Paul Collinson, Rune Bjørneklett, Kjell Vikenes, Trude Steinsvik, Øyvind Skadberg, Øistein R Mjelva, Alf Inge Larsen, Vernon V S Bonarjee, Nicholas L Mills, Kristin M Aakre. Exploring Sex-Specific High-Sensitivity Cardiac Troponin Thresholds for Rule-Out of Non-ST-Elevation Myocardial Infarction. Clinical Chemistry, Volume 72, Issue 8, August 2026, Pages 868–879. https://doi.org/10.1093/clinchem/hvag030

Juexiao Sherry Wang, C J Battey, Kyle Trettin, Ravi Patel, Anu Srinivasan, Janani Saikumar, Divya Kushnoor, Ben F Habermeyer, Sangita Ganesh, Nafei Xu, Nathaniel Friedrich, Summer Pierson, Helen Wan, Heather LaBreche, Genevieve M Gould, Dale Muzzey. Simultaneous Prenatal cfDNA Screening of Aneuploidy, Recessive Single-Gene Conditions, and Fetomaternal Blood Compatibility. Clinical Chemistry , Volume 72, Issue 6, June 2026, Pages 679–691. https://doi.org/10.1093/clinchem/hvag005

Ryan Pearce, Leslie J Donato, Vlad C Vasile, Allan S Jaffe, Jeffrey W Meeusen. From Pooled Cohorts to PREVENT: A Perspective for Clinical Laboratorians. Clinical Chemistry, Volume 72, Issue 7, July 2026, Pages 814–816. https://doi.org/10.1093/clinchem/hvag044

Anna C H Hoge, Thomas E Grys, Erin H Graf. Disseminated Coccidioidomycosis in Immunocompetent Hosts: Opportunities for Increased Recognition and Timely Diagnosis. Clinical Chemistry , Volume 72, Issue 5, May 2026, Pages 575–582. https://doi.org/10.1093/clinchem/hvaf187

Ann M Moyer, Emma Lundquist, Emily K Thoreson, Michelle L Kluge, Katrina E Kotzer, Elyse M Love, Heather L Glessner, Sarah K Arneson, Loralie J Langman, Linnea M Baudhuin, John Logan Black. DPYD Sequencing Identifies More Clinically Relevant Variants as Compared to Targeted Genotyping. Clinical Chemistry, Volume 72, Issue 6, June 2026, Pages 662–669. https://doi.org/10.1093/clinchem/hvag007 .

Lisa A Lansdon, Binu Porath, Mari Mori, David T Miller, Diane Dunham Drexler, Catherine Wattenberg, Morgan Richardson, Robert D Steiner, Peter J Freeman. Universal Presence of Gene/Variant Nomenclature Errors in Journal Manuscript Submissions. Clinical Chemistry , Volume 72, Issue 6, June 2026, Pages 652–661. https://doi.org/10.1093/clinchem/hvag010

Patrick M Bossuyt, Tze Ping Loh, Katy Bell, Sally Lord, Andrea R Horvath. Frameworks of Health Outcomes for Performance Specifications in Laboratory Medicine. Clinical Chemistry , Volume 72, Issue 5, May 2026, Pages 546–553. https://doi.org/10.1093/clinchem/hvag014

Grace Drew, Colleen S Kraft, Nirja Mehta. Fecal Microbiota Therapy: Clinical Laboratory Testing and Metabolomic Approaches for Donor Screening, Product Assessment, and Patient Monitoring. Clinical Chemistry , Volume 72, Issue 5, May 2026, Pages 554–563. https://doi.org/10.1093/clinchem/hvaf156

Andrea L Benedet, Burak Arslan, Kubra Tan, Hanna Huber, Ilaria Pola, Guglielmo Di Molfetta, Hlin Kvartsberg, Anna Orduña Dolado, Shorena Janelidze, Kaj Blennow, Henrik Zetterberg, Oskar Hansson, Pedro Rosa-Neto, Nicholas J Ashton. Diagnostic Value of Serum p-tau217 in Alzheimer Disease: Equal to Plasma in Levels and Clinical Utility? Clinical Chemistry , Volume 72, Issue 2, February 2026, Pages 303–315, https://doi.org/10.1093/clinchem/hvaf162

Denise M O'Sullivan, Gerwyn M Jones, Manca Zolnir-Dovc, Richard Phillips, Rejoice Arthur, Bariki Mtafya, Daniel Adon Mapamba, Daniela Maria Cirillo, Ewa Augustynowicz-Kopeć, Mei Mei Ho, Belinda Dagg, Sven O Friedrich, Francesca Colavita, Antonella Vulcano, Prince Asare, Dorothy Yeboah-Manu, Timothy D McHugh, Jim F Huggett. Methods to Improve Confidence in the Accuracy of Molecular Testing for Multidrug-Resistant Tuberculosis. Clinical Chemistry, Volume 72, Issue 3, March 2026, Pages 390–397. https://doi.org/10.1093/clinchem/hvaf178

Thomas J S Durant, Seung Joo Lee, Sarah N Dudgeon, Elizabeth Knight, Brent Nelson, H Patrick Young, Lucila Ohno-Machado, Wade L Schulz. Quantum Machine Learning and Data Re-Uploading: Evaluation on Benchmark and Laboratory Medicine Data Sets. Clinical Chemistry , Volume 72, Issue 4, April 2026, Pages 451–460. https://doi.org/10.1093/clinchem/hvaf192