The Feldman Protocol

In this episode of The Feldman Protocol, how well do conventional cardiovascular risk metrics actually identify who is truly at risk for a heart attack decades before it happens? Cardiologist Arthur Agatston (MD) makes the case for coronary calcium scoring as an early detection tool, discusses the natural history of atherosclerotic plaque, revisits key moments in lipid science history, explores why stent placement in asymptomatic patients presents a more complex picture than intuition suggests, and shares observations on the evolving role of CT angiography and AI-assisted plaque analysis. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/50` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Cold open & introduction 7:46 – Arthur's path into medicine 18:59 – Early cardiology & clinical trials 27:47 – Lipid science history & Ancel Keys 39:04 – Rabbit studies & lipoprotein discovery 47:15 – Ultra-fast CT arrives at Sinai 55:26 – Collateral vessels & total occlusion 1:00:00 – Ischemia trial: stents vs. medical therapy 1:05:01 – Back to the CAC origin story 1:13:09 – Soft vs. calcified plaque progression 1:21:40 – FH patient with zero CAC score 1:26:53 – The Agatston score is named 1:33:51 – Power of zero & plaque burden 1:39:35 – CAC vs. CT angiogram explained 1:44:19 – Resistance to new imaging technology 1:48:34 – Nutrition interest in the 1990s 1:49:25 – Heart Lung AI & plaque ratio research 1:51:11 – Closing reflections #FeldmanProtocol #DaveFeldman #ArthurAgatston #CoronaryCalcium #HeartHealth #Atherosclerosis #CardiacImaging #CACScore #LDL #Lipids #PlaqueBiology #CTAngiogram #CardiologyResearch #LowCarbDiet #LeanMassHyperResponder #HeartDiseasePrevention #LipidScience #CardiovascularResearch

In this episode of The Feldman Protocol, how does insulin influence cancer cell behavior — and what does that mean for metabolic approaches to the disease? Dave sits down with Isabella Cooper (PhD) to explore the glucose-ketone index and its practical limits, the role of glutamine alongside glucose in cancer metabolism, how mitochondrial dysfunction and cardiolipin loss may relate to tumor progression, the case for high-dose intravenous vitamin C, osteocyte biology and the surprising systemic roles of osteocalcin, and what makes a rigorous research culture. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/49` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Cold open & intro 1:08 – Cancer metabolism overview 2:24 – Glucose-ketone index explained 5:01 – Lean mass hypersponders & glucose 9:18 – Acetone measurement & respiration 13:49 – Insulin, ketones & cancer signaling 19:05 – Growth factors & VEGF discussion 25:29 – Stomach acidity & nutrient absorption 32:08 – How cancer cells originate 35:43 – Cardiolipin, melatonin & apoptosis 43:05 – Diet quality & food as function 52:14 – Chemotherapy & metabolic protocols 1:03:36 – Patient outcomes & biopsy risks 1:14:32 – IV vitamin C trial findings 1:22:07 – Ideal cancer metabolism trial design 1:29:36 – Sunlight, melanin & mitochondria 1:37:20 – Osteocyte biology & osteocalcin 1:46:43 – Research culture & scientific rigor 1:54:36 – Most underappreciated biomarker #FeldmanProtocol #DaveFeldman #IsabellaCooper #CancerMetabolism #KetogenicDiet #Mitochondria #Insulin #GlucoseKetoneIndex #Osteocalcin #IntravenousVitaminC #Ketosis #MetabolicHealth #LowCarbScience #CancerResearch #Cardiolipin #Osteocytes #BloodWork #Hyperinsulinemia #MitochondrialHealth #PodcastScience

In this episode of The Feldman Protocol, what does beta-hydroxybutyrate between meals actually reveal about a person's insulin state — and why might that matter for understanding chronic disease risk? Dave sits down with Isabella Cooper (PhD), a biochemistry and pathophysiology scientist whose research spans assay quality control, hyperinsulinemia detection, ketone thresholds, mitochondrial function, and the lipid energy model, making the case that personalized insulin thresholds — not population-wide cutoffs — may be key to identifying subclinical metabolic dysfunction.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/48` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Cold open & intro1:06 – Isabella's background & credentials3:05 – East-meets-West medicine upbringing5:43 – Ballet, modeling & low-carb insights6:36 – Industrial design degree & lab thinking8:58 – Assay quality problems in undergrad lab12:08 – Coefficient of variation explained17:01 – Standardizing vortex & sample handling27:30 – Back to timeline: the 15-year gap39:52 – Pregnancy, diapers & toxicology deep dive53:06 – Old physiology papers vs modern science1:00:05 – Osteocalcin hypothesis & being wrong1:06:48 – Ben Bikman, mitochondria & insulin1:19:40 – Headwinds for low-carb research1:34:19 – Personalized insulin threshold concept1:41:28 – Beta-hydroxybutyrate as insulin surrogate1:51:44 – Leptin, IGF-1 & multi-marker detection2:09:09 – Subclinical hyperinsulinemia marker cluster2:14:20 – Fasting, lipid dynamics & VLDL traffic#FeldmanProtocol #DaveFeldman #IsabellaCooper #Hyperinsulinemia #Ketosis #Mitochondria #MetabolicHealth #InsulinResistance #BetaHydroxybutyrate #LowCarb #ChronicDisease #LipidEnergyModel #AssayQuality #KetoneThreshold #LaboratoryScience #Bioenergetics #BloodTesting #Inflammation

In this episode of The Feldman Protocol, how much does metabolic health shape cardiovascular risk beyond what standard lipid markers can reveal? Dave Feldman sits down with Scott Murray (MD), a UK-based interventional cardiologist, to explore plaque imaging and its limitations, the role of visceral and perivascular fat in heart disease, the lipid energy model and lean mass hyper-responders, cardiac fuel metabolism and heart failure with preserved ejection fraction, and the challenges of conducting and interpreting cardiovascular trials. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/47` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Cold open & Scott's intro 14:21 – Scott's cardiology practice 17:28 – Invasive vs. CT angiography 24:49 – Collaterals & microvascular function 34:31 – Glycocalyx & endothelial health 40:28 – Perivascular fat & imaging 51:14 – Imaging, CAC, and plaque noise 1:00:04 – Lipid hypothesis & population context 1:07:05 – CT plaque measurement variability 1:19:42 – Perivascular inflammation & Caristo scoring 1:29:07 – Lipid energy model discussion 1:49:43 – LP(a), acute-phase markers & reverse causation 2:05:01 – LMHR study timeline & next scans 2:22:57 – Heart fuel preference & HFpEF 2:39:08 – PCSK9 trials & all-cause mortality 2:52:06 – Run-in periods & trial design concerns 3:05:00 – Context, guidelines & patient conversations 3:17:35 – GLP-1 peptides & obesity biology 3:26:28 – Where to find Scott & closing thoughts #FeldmanProtocol #DaveFeldman #ScottMurray #PreventiveCardiology #HeartHealth #LipidHypothesis #LeanMassHyperResponder #CTAngiography #PlaqueImaging #CardiovascularResearch #MetabolicHealth #LipidEnergyModel #HeartFailure #LPa #GLP1 #TrialDesign #Cardiology #LowCarb #BloodWork

In this episode of The Feldman Protocol, what actually drives cardiovascular disease in a metabolically healthy, lean individual — and is elevated LDL the most important variable to consider? Darius Sharpe (ER nurse and lean mass hypersponder community member) discusses his unexpected CAC score at age 38, his theory on postprandial glucose and vascular damage, a personal episode of atrial fibrillation, the Keto CTA study's Clearly data controversy, and what ER nurses observe firsthand about metabolic illness. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/43` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Cold open & CAC score reveal 4:51 – Darius's CAC scan background 9:07 – First-phase insulin response explained 15:47 – CAC result context & vessel findings 22:09 – Darius investigates his own cardiac risk 33:43 – Atrial fibrillation episode & AFIB physiology 43:28 – Electrolytes, magnesium, and sodium discussion 51:04 – Stress tests vs. imaging: a patient case 58:01 – Metabolic syndrome underdiagnosis in hospitals 1:03:09 – Dave's diet experiments & LMHR data 1:09:18 – Fat bomb experiment: NMR findings 1:20:53 – Lipid energy model & structural hypothesis 1:30:37 – Keto CTA: plaque associations & progressors 1:39:41 – Clearly data controversy & scientific transparency 1:51:55 – Glucose, hyperglycemia, and plaque theory 2:05:22 – Raw data release & cards on the table 2:15:01 – ER realities & medication safety 2:29:07 – Lifestyle, habits, and the ER patient perspective 2:39:10 – Where to find Darius & closing thoughts #FeldmanProtocol #DaveFeldman #DariusSharpe #LeanMassHypersponder #KetoCTA #CACScore #AtrialFibrillation #PostprandialGlucose #MetabolicSyndrome #LipidEnergyModel #CardiovascularHealth #CGM #LDL #InsulinResponse #ERNurse #BloodTesting #HeartHealth #NMRPanel

In this episode of The Feldman Protocol, how well does the prevailing understanding of LDL and cardiovascular disease hold up under close scrutiny? Dave sits down with Malcolm Kendrick (MD) — author, researcher, and longtime cardiovascular disease skeptic — who challenges key assumptions across trial methodology, observational data, Mendelian randomization, clinical trial blinding, nitric oxide's role in vascular health, and the response-to-injury model of atherosclerosis.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/46` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Introduction & cold open1:11 – Malcolm Kendrick's background6:02 – Early contrarian tendencies in medicine16:48 – International cholesterol skeptic network22:13 – Shifting LDL targets over decades39:05 – FH, heterozygous vs. homozygous49:35 – Examining pharmaceutical trial evidence57:00 – Clinical trial blinding & composite endpoints1:07:27 – Data transparency & CTT access questions1:23:11 – Statins, nitric oxide & plausible mechanisms1:37:34 – Mendelian randomization discussed1:54:43 – Audience questions: ApoB & endothelial injury2:05:24 – Kendrick's cardiovascular disease model2:19:44 – Shared models: vascular repair & hemostasis2:38:39 – The Daily Mail lawsuit: origins2:47:32 – Five-year legal battle & court proceedings3:00:01 – CTT emails & trial methodology concerns3:17:29 – LMHR study update & CLEARLY retraction3:33:23 – Where to find Malcolm Kendrick#FeldmanProtocol #DaveFeldman #MalcolmKendrick #CardiovascularDisease #LDLCholesterol #LipidHypothesis #ClinicalTrials #NitricOxide #Atherosclerosis #StatinResearch #HeartHealth #LeanMassHyperresponder #CholesterolDebate #ApoB #MetabolicHealth #EvidenceBasedMedicine #TrialMethodology #Cholesterol

In this episode of The Feldman Protocol, what does it take to recognize and address a compulsive relationship with food — and why does that recognition matter so much? Jen Unwin (clinical and health psychologist) joins Dave to explore the psychology of hope in medical settings, her personal history with carbohydrate-driven food behaviors, the evidence behind ultra-processed food addiction as a proposed clinical category, the WHO/ICD recognition process, GLP-1 medications as one potential tool, and why social context and proximity to trigger foods shape outcomes for so many people.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/45` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Introduction & cold open1:13 – Jen's background in psychology5:44 – Path to clinical training in Manchester12:47 – Hope as a clinical concept21:28 – Positive psychology & the nun study27:02 – Hope's influence on David Unwin's practice35:23 – Jen's personal food history43:02 – Discovering low-carb & the turning point52:22 – Food addiction: Dave's french fry story1:02:47 – Seeking official recognition of food addiction1:09:01 – Building expert consensus on terminology1:15:55 – Treatment outcomes & published research1:27:47 – Comparing food addiction to tobacco history1:36:05 – Proximity, social pressure & behavior change1:47:08 – Behavioral vs. substance-based framing1:54:52 – Prevalence data & retired athlete findings2:02:23 – Audience questions & GLP-1 medications2:33:39 – Nutrient density, protein, and food as fuel2:39:41 – Where to find Jen & closing remarks#FeldmanProtocol #DaveFeldman #JenUnwin #FoodAddiction #UltraProcessedFood #HopeInMedicine #PositivePsychology #LowCarb #BehaviorChange #DSM #FoodAddictionRecognition #CarbohydrateAddiction #GLP1 #NutrientDensity #MentalHealth #SolutionFocused #MetabolicHealth #Keto

In this episode of The Feldman Protocol, how does one family doctor's decades-long frustration with a "progressive, incurable" disease lead to a fundamentally different approach to patient care? Dave Feldman and David Unwin (MD) explore the pivotal 2012 patient encounter that reshaped Unwin's practice, the psychology of behavior change and food addiction, real-world data from a 10,000-patient NHS cohort, collaborative medicine versus authoritarian care, GLP-1 drugs as a last resort, and AI's emerging role in clinical decision-making. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/44` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Introduction & cold open 1:24 – David Unwin's background 13:07 – Generational health trends observed 20:19 – Conventional medicine & early career 39:14 – The art vs. science of medicine 52:28 – The ACCORD study discussed 1:04:45 – The 2012 pivotal patient encounter 1:17:13 – Publishing the first 18-patient audit 1:30:06 – Unexpected behavioral changes on diet 1:45:09 – Collaborative medicine & patient partnership 2:02:32 – Evolutionary context for modern diet 2:13:06 – Food addiction & maintenance challenges 2:35:12 – GLP-1 drugs: a nuanced discussion 2:47:23 – Questions from the desk 3:09:27 – Unwin's real-world remission data 3:16:03 – AI in medicine & society 3:44:36 – Technology, freedom & human adaptability 3:59:46 – Closing & where to find David Unwin #FeldmanProtocol #DaveFeldman #DavidUnwin #LowCarb #MetabolicHealth #Type2Diabetes #DiabetesRemission #BehaviorChange #FoodAddiction #CollaborativeMedicine #NHSData #GLP1 #NutritionalScience #InsulinResistance #RealWorldData #PublicHealthCollaboration #LowCarbGP #AIInMedicine #FamilyMedicine

Part 1 of 2In this episode of The Feldman Protocol, what can a quarter-century of emergency medicine experience reveal about the everyday habits quietly shaping metabolic health outcomes? Darius Sharpe (ER nurse and former paramedic with 24 years in emergency medicine) makes the case that postprandial glucose excursions deserve far more clinical attention, discusses his personal glucose experiments after a low-carb reintroduction of fast food, shares observations on hospital nutrition practices, and weighs in on the calories-in/calories-out vs. carbohydrate-insulin debate.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/42` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Cold open & introduction1:10 – Darius introduces himself3:42 – Path from EMT to ER nurse12:09 – Recognizing atypical heart attack symptoms16:07 – Time is tissue: stroke & MI urgency24:33 – Patterns Dave saw responding to 911 calls40:25 – Darius's personal health & family history54:44 – Early lipid labs and what they showed1:01:11 – Nursing school glucose discovery1:13:32 – The In-N-Out glucose experiment series1:21:42 – Joining the LMHR community1:31:40 – Metabolic illness observations during 2020–20221:45:43 – First CGM and self-experimentation1:51:14 – Keto week vs. high-carb week: OGTT comparison1:59:39 – Defining low-carb, keto, and net vs. total carbs2:19:36 – Calories vs. insulin: what both sides get right2:30:58 – Hospital food, juice, and postprandial glucose2:44:29 – Bedside patient education and CGM advocacy#FeldmanProtocol #DaveFeldman #DariusSharpe #MetabolicHealth #BloodSugar #PostprandialGlucose #LeanMassHyperResponder #LMHR #LowCarb #KetogenicDiet #CGM #ContinuousGlucoseMonitor #EmergencyMedicine #ERNurse #InsulinResistance #Cholesterol #HeartHealth #StrokeAwareness #HospitalNutrition

In this episode of The Feldman Protocol, can a practicing family physician's personal health crisis reshape the dietary advice he gives to thousands of patients? Ken Berry (MD) makes the case for low-carbohydrate approaches in managing metabolic conditions, shares his path from rural Tennessee to family medicine, discusses founding the American Diabetes Society as an alternative institution, explores the debate around long-term ketosis and fasting insulin, and joins Dave and audience members in examining how to rebuild trust in medical and scientific institutions. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/40` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Cold open & introduction 1:51 – Ken Berry's background in medicine 8:08 – Path from rural Tennessee to med school 16:03 – Ken's health during his early career 23:01 – Shifting away from standard dietary guidelines 33:42 – Patient signals and expanding the practice 42:17 – Starting a YouTube channel 54:21 – "Lies My Doctor Told Me" and colleague pushback 1:00:18 – Founding the American Diabetes Society 1:05:00 – Audience Q&A begins 1:08:53 – Discussion of long-term ketosis markers 1:18:31 – Talking to loved ones about diet 1:29:14 – Nutrition education in medical schools 1:39:47 – Restoring trust in medical institutions 1:47:00 – Semmelweis, paradigm shifts & patience 1:55:40 – Long-term ketosis safety & ketone measurement 2:09:10 – Blood work as a snapshot: context matters 2:30:28 – Dietary flexibility, travel, and glucose spikes 2:51:05 – Closing remarks & where to find Ken Berry #FeldmanProtocol #DaveFeldman #KenBerry #LowCarbDiet #KetogenicDiet #CarnivoreDiet #MetabolicHealth #BloodSugar #InsulinResistance #DiabetesManagement #FamilyMedicine #NutritionScience #ProperHumanDiet #CGM #CholesterolCode

In this episode of The Feldman Protocol, can elite athletes truly thrive on fat alone — with zero carbs? Dave sits down with Casey Ruff (personal trainer, nutrition coach, and host of Boundless Body Radio) to explore his journey from gym kid to keto rebel, high-intensity training principles, a rogue low-carb experiment inside a corporate fitness company that produced 732 lbs of fat loss, the LMHR study saga, carnivore adaptation and anxiety relief, and a surprising email from the American Heart Association. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/39` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 3:17 – Casey's ice hockey obsession 8:05 – A punch that changed everything 12:38 – Two years in Brazil as a missionary 17:03 – From architecture dreams to personal training 21:06 – Finding his calling at the gym 28:51 – High intensity training explained 36:57 – Why sport-specific training is a myth 39:02 – Metabolic carts & the RER deep dive 43:01 – The Biggest Loser metabolic damage case 46:24 – Calories in/out: why it failed everyone 50:25 – Nina Teicholz & The Big Fat Surprise 54:07 – Bonking, glycogen, and fat adaptation 58:10 – Butter-fed athletes & the keto revelation 1:04:13 – Casey's fasted hockey game story 1:06:07 – Going rogue with Diet Doctor meal plans 1:14:02 – Getting the nutrition certification 1:17:17 – The contest winner who changed everything 1:20:19 – 732 lbs lost, 98.1% from fat 1:27:33 – Did results hold after the contest? 1:33:27 – Starting Boundless Body podcast in 2020 1:41:25 – On being a natural podcast host 1:52:17 – The pandemic pivot to virtual training 1:59:08 – Carnivore and the vanishing anxiety 2:04:31 – The LMHR Match Analysis saga begins 2:16:26 – Low Carb Denver 2023 collective gasp 2:23:22 – Dave reveals new Heartflow re-analysis 2:29:35 – The movie & Robin's bipolar decision 2:31:37 – The AHA misinformation email 2:42:14 – Prepping for Arthur Agatston 2:48:42 – Fat adaptation and hockey performance 2:55:39 – Travel strategies: fasting vs. carnivore snacks 2:59:08 – Changing his mind: strict carnivore or not? 3:05:36 – Where to find Casey #FeldmanProtocol #DaveFeldman #CaseyRuff #LowCarbLife #KetoDiet #CarnivoreDiet #FatAdaptation #HighIntensityTraining #LMHRStudy #CholesterolCode #MetabolicHealth #SeedOils #HeartHealth #NutritionCoach #EnduranceSport #BloodWork #Ketosis #BoundlessBodyRadio

In this episode of The Feldman Protocol, can a for-profit assisted living home actually send residents back home healthier than when they arrived? Hal Cranmer (assisted living owner and metabolic health advocate) makes the case that ketogenic and carnivore nutrition, resistance training, hyperbaric oxygen therapy, and disciplined deprescribing can reverse diabetes, restore cognition, and rebuild independence — even in residents in their 80s and 90s. Dave and Hal also cover dementia and sugar addiction, the business model of senior care, and the future of AI in medicine. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/38` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 3:06 – The assisted living industry spectrum 4:41 – "End of the line" vs. recovery mindset 7:27 – How crisis moments force placement decisions 10:41 – From real estate to assisted living 15:42 – Running the first home: Blue Sky Manor 22:11 – Competing on service, not price 25:04 – Moving the whole family to Arizona 36:39 – Why referrals are nothing like renting 44:12 – Owner presence builds family trust 47:37 – The Berlin airlift resident who went home 51:05 – Dave on the pay-it-forward feeling 54:19 – Finding a unique selling proposition 56:05 – The vegan nutrition experiment 1:03:55 – Hal tries carnivore himself 1:07:42 – Two-year digestive problem gone in two weeks 1:10:11 – Sarcopenia: the underrated elderly crisis 1:17:07 – Dr. Dale Bredesen and the Alzheimer's protocol 1:23:01 – Why steak gets judged but cake doesn't 1:30:17 – Rolling out keto in the homes 1:34:17 – Maria Emmerich cookbooks change everything 1:40:45 – Audience questions: most surprising therapy 1:43:21 – How hyperbaric oxygen therapy works 1:53:14 – What residents actually eat each day 1:57:01 – Total carbs, not net carbs — and 65 names for sugar 2:01:36 – Adherence after leaving the home 2:11:44 – Diabetes reversal and dementia as type 3 diabetes 2:19:42 – Working with doctors to reduce medications 2:25:57 – The Dr. Tro Kalagian research study begins 2:33:32 – Dave raises the cholesterol question 2:39:37 – Polypharmacy, drug interactions, and deprescribing 2:47:51 – AI, objectivity, and open-source health data 3:00:01 – Engineering culture vs. medical hierarchy 3:09:54 – Mental attitude and fighting dementia diagnosis 3:15:03 – Carnivore diet and dramatically fewer illnesses 3:18:17 – Fewer UTIs and infections on keto diet 3:18:49 – Where to find Hal Cranmer #FeldmanProtocol #DaveFeldman #HalCranmer #AssistedLiving #KetoDiet #CarnivoreDiet #MetabolicHealth #Dementia #Alzheimer's #DiabetesReversal #Sarcopenia #HyperbaricOxygen #LowCarb #ElderCare #BrainHealth #ProteinIntake #Deprescribing #HealthSpan #LongevityWellness

In this episode of The Feldman Protocol, how does a physician's personal and professional crucible shape an unconventional approach to metabolic medicine? Annette Bosworth (MD) joins Dave to discuss her legal battles and U.S. Senate campaign, her mother's experience with a ketogenic dietary intervention, the behavioral psychology behind lasting dietary change, her structured 21-day intensive program, observations on combining nutritional ketosis with low-dose GLP-1/GIP therapy, and her husband's sudden vision loss diagnosis.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/37` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Cold open & introduction16:20 – Petition signatures & legal exposure25:49 – Arrest timing and felony charges33:42 – Sentencing and community service41:22 – Medical board fight continues49:14 – Discovering the ketogenic diet57:52 – Mother's six-week dietary experiment1:03:44 – Meeting Dr. Westman; going all-in1:09:20 – Group accountability and behavior change1:16:01 – Metabolic damage and recovery timelines1:23:07 – Keto momentum in medicine and research1:33:37 – The 21-day intensive boot camp1:44:04 – Extension class and low-dose tirzepatide1:56:41 – Case series, IRB, and Own Your Labs2:06:17 – Publishing research and the literature gap2:14:49 – Own Your Labs advisor portal discussion2:23:26 – Chad's sudden vision loss2:36:53 – Where to find Annette & closing thoughts#FeldmanProtocol #DaveFeldman #AnnetteBosworth #DrBoz #KetogenicDiet #MetabolicHealth #LowCarb #GLP1 #Tirzepatide #InsulinResistance #BehaviorChange #ChronicDisease #Autophagy #NutritionalKetosis #FunctionalMedicine #PatientCare #MedicalEducation #HealthCoaching

In this episode of The Feldman Protocol, what does a physician's journey through rural medicine, corporate bureaucracy, and scientific controversy reveal about how the healthcare system handles innovation? Dave Feldman sits down with Annette Bosworth (MD), an internal medicine physician and author, who discusses her origin story in small-town South Dakota, the role of lifestyle factors in patient outcomes, her early adoption of lower-carbohydrate approaches, and the challenges she faced practicing outside conventional medical structures. Dave also shares an extended, candid update on the LMHR study retraction and the competing AI plaque analyses.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/tfp/36` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://thefeldmanprotocol.com`⏱ Chapters0:00 – Cold open & intro7:41 – Decision to pursue medicine14:23 – Early nursing home experience28:01 – Choosing internal medicine41:02 – Residency: Salt Lake City & shock trauma51:39 – First outpatient practice challenges1:00:45 – Discovering lower-carb approaches1:05:20 – Lab letters & patient engagement1:09:47 – The Feldman Protocol origin1:24:30 – LMHR study: competing analyses1:30:05 – Power of zero CAC & Heartflow data1:39:34 – The retraction process explained1:49:26 – Annette's removal from corporate medicine1:55:00 – Serving Native American youth in shelters2:00:49 – Iron deficiency, pica, and IV iron2:06:34 – Medicaid investigation & financial toll2:11:18 – Living in an RV & running for U.S. Senate#FeldmanProtocol #DaveFeldman #AnnetteBosworth #LeanMassHyperResponder #InternalMedicine #LowCarb #HeartHealth #PlaqueStudy #MedicalResearch #PatientAdvocacy #KetoDiet #BloodWork #CholesterolDebate #PhysicianBurnout #NutritionScience #CardiovascularHealth #CitizenScience

In this episode of The Feldman Protocol, how much does mitochondrial energy metabolism shape long-term health outcomes — and what does that mean for how we interpret cardiovascular, immune, and metabolic research? Dave sits down with Chris Masterjohn (PhD) to explore his mitochondrial testing company and what enzyme-complex patterns may reveal about individual nutritional needs, his longstanding model of LDL oxidation and plaque formation, the emerging pressure-based hypothesis in Crohn's disease research, concerns he raises about polyunsaturated fatty acids and long-term trial design, and the state of peer review and research transparency. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/35` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 0:00 – Cold open & intro 1:13 – Chris introduces his mitochondrial testing work 3:36 – ATP, LDL receptors & cellular energy 8:32 – Idiosyncratic nutritional needs & CoQ10 case 14:06 – Exercise, longevity & gymnast data 22:18 – Biomechanics, T cell activation & cancer hypothesis 28:43 – Crohn's disease, pressure hypothesis & diet 38:29 – Paleo, Weston Price & dietary history 47:25 – Causal inference, language in research & peer review 58:28 – Dave's early lipid energy model presentation 1:01:33 – Chris's longstanding LDL oxidation model 1:09:04 – Transcytosis, innate immunity & plaque dynamics 1:30:07 – Monogenic FH, Bradford Hill & LDL debate 1:49:14 – The KETO-CTA study & plaque progression data 1:58:15 – Seed oils: history, trial design & oxidative liability 2:24:01 – Short vs. long-term trial evidence on seed oils 2:46:02 – Research incentives, NIH funding & open data 2:54:35 – Audience questions, diet & supplements 3:00:01 – Where to find Chris Masterjohn #FeldmanProtocol #DaveFeldman #ChrisMasterjohn #Mitochondria #LDL #Cholesterol #SeedOils #Atherosclerosis #LipidHypothesis #CrohnsDisease #NutritionScience #PeerReview #MetabolicHealth #CardiovascularResearch #LipidEnergyModel #PUFA #VitaminE #ResearchTransparency #Longevity

In this episode of The Feldman Protocol, Dave Feldman sits down with Peter Ballerstedt (PhD) — forage agronomist and founder of Grass Based Health.🔥 This episode is sponsored by us --Own Your Labs 👉 `https://ownyourlabs.com/sp/34` Private blood testing services🩸Over 300 blood tests💰Extremely affordable❤️ We love our customers(Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏)🔗 CONNECT WITH DAVE FELDMAN:Main Channel: `https://youtube.com/@realDaveFeldman`X/Twitter: `https://x.com/realDaveFeldman`Instagram: `https://instagram.com/realDaveFeldman`Website: `https://feldmanprotocol.com`

In this episode of The Feldman Protocol, can the environment you go home to matter more than the brain injury itself? Tommy Wood (MD PhD) makes the case that how you use your brain is the primary driver of how it functions — then digs into CTE mechanics, the myth of the brain "sloshing" in the skull, why animal models of concussion may fundamentally miss the point, ketogenic diets and mental health, AI as orthotic vs. prosthetic, and why obsessing over sleep data might hurt you more than poor sleep. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/33` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 3:04 – Tommy's background & book origin 6:03 – Medicine vs. research career path 9:27 – UK vs. US medical debt & freedom 13:40 – How Tommy became a brain person 17:14 – The Stimulated Mind: core themes 21:37 – Use it to improve it: the science 26:34 – Brain specialization trade-offs 34:32 – Human cognition: 10 bits/second 39:06 – Blindfolded Rubik's Cube & subroutines 43:31 – Myth of multitasking 46:03 – Neonatal brain injury research 50:09 – Therapeutic hypothermia explained 54:44 – Home environment predicts recovery 58:39 – Rugby vs. American football & CTE 1:00:19 – What CTE actually is 1:06:40 – Brain doesn't slosh — the real mechanism 1:11:05 – Why animal concussion models fail 1:17:44 – The Q-collar: does it work? 1:21:33 – Valsalva & protecting the brain 1:28:32 – Nutrition & the brain: three levers 1:38:28 – Ketogenic diet: then vs. now 1:46:05 – Energy availability U-shaped curve 1:51:26 – Insulin resistance & fat cell dynamics 1:58:48 – Calories in/out vs. carb-insulin debate 2:03:37 – The BROAD Study & behavior change 2:12:36 – AI & LLMs: net benefit or detriment? 2:17:09 – Orthotic vs. prosthetic framework 2:21:08 – MIT essay study unpacked 2:33:20 – Google effect & changing memory use 2:40:11 – AI slop flooding academia 2:47:15 – Artificial sweeteners & neurotoxicity 2:50:04 – Why sleep is critical for the brain 2:52:11 – Orthosomnia: when sleep tracking backfires 2:57:58 – Where to find Tommy & the book #FeldmanProtocol #DaveFeldman #TommyWood #BrainHealth #Neuroscience #CTE #Concussion #KetogenicDiet #Ketones #AnimalModels #SleepScience #AIAndTheBrain #CognitiveFitness #Dementia #NeonatalBrainInjury #MetabolicHealth #NutritionScience #BrainTraining #PublishOrPerish #TheStimulatdMind

In this episode of The Feldman Protocol, can a diet of almost exclusively meat actually support world-record athletic performance while raising serious questions about conventional cardiovascular risk? Shawn Baker (MD) traces his path from professional rugby and military trauma surgery to pioneering the carnivore movement, makes the case for carnivore as a powerful elimination diet for autoimmune and inflammatory disease, and engages Dave in a nuanced debate on LDL, plaque imaging data, gut microbiome myths, and the politics of nutrition research. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/32` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 3:01 – Shawn's early path to medicine 4:47 – Dropping med school for pro rugby 6:12 – Military service & trauma surgery 9:44 – Back to the military & civilian practice 11:09 – Personal health decline & first diet shift 14:58 – Discovering paleo & low-carb 17:31 – Why Shawn moved beyond paleo 23:01 – First exposure to carnivore (zero-carb) 29:41 – Going all-in on carnivore in 2016 35:23 – Plant-based vs. carnivore athletes 40:20 – The Joe Rogan appearance that changed everything 44:29 – Getting first bloodwork: testosterone & A1C controversy 51:27 – Fasting glucose on keto: diabetic or adapted? 55:15 – OGTT, fat adaptation & continuous monitors 57:37 – Birth of MeatRx & collecting anecdotal data 1:04:05 – Cholesterol: Dave asks Shawn's real view 1:09:03 – The KETO-CTA study & the Clearly curveball 1:15:12 – Will the 5-year scans show LDL-plaque links? 1:19:43 – Informed consent when cholesterol spikes on carnivore 1:27:29 – Shawn's Europe "cheat" & a month of whole-food carbs 1:33:37 – The viral steak-eating videos explained 1:37:07 – Debates with vegan activists 1:42:06 – Carnivore for autoimmune & inflammatory disease 1:46:46 – Rivero: building a 50-person clinical team 1:53:47 – Carnivore variations: keto-style, dairy & organ meat 2:00:16 – 10 years nearly zero organ meat: any deficiencies? 2:02:25 – Allegations of PEDs: Shawn's full response 2:08:14 – Shifting toward sprinting & masters track 2:13:21 – Ex-carnivores & the "sustainability" criticism 2:23:51 – Carnivore as elimination diet: the Clue game analogy 2:26:30 – Gut microbiome, fiber & metabolic flexibility 2:34:07 – GLP-1 drugs, LDL, and the BMI confounder 2:39:35 – Metabolic health as the real cardiovascular driver 2:51:52 – Imaging noise floors & what the data really shows 2:58:01 – Homozygous FH, cumulative LDL & study power 3:04:55 – Designing the TRIAD study & goal-post shifting 3:11:37 – Where the lipid hypothesis holds—and where it doesn't #FeldmanProtocol #DaveFeldman #ShawnBaker #CarnivoreDiet #LDLCholesterol #HeartHealth #MetabolicHealth #LowCarbDiet #KetoDiet #Atherosclerosis #PlaqueProgression #AutoimmuneDisease #GutHealth #AthleteNutrition #MastersAthletics #NutritionResearch #AnimalBasedDiet #CitizenScience #Lipidology #KetoCTA

In this episode of The Feldman Protocol, can a ketogenic diet actually build a championship physique — or does elite bodybuilding demand carbs? Robert Sikes (natural pro bodybuilder and founder of Keto Brick) makes the case that fat adaptation outperforms conventional prep, sharing his journey through eating disorders, the origins of Keto Brick, his seven-phase protocol, reverse dieting, and the debate around calories vs. carbohydrate-insulin models. 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/31` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` ⏱ Chapters 4:20 – Dave asks Robert to introduce himself 5:23 – Early life & farm-strong beginnings 6:19 – Starting bodybuilding as a skinny kid 8:44 – Eating 6,000 calories to bulk up 10:16 – First bodybuilding competition in college 12:32 – The bulk/cut cycle explained 16:17 – Losing 80 lbs in 12 weeks 16:52 – Eating disorders after the first show 19:47 – Searching for a better dietary approach 22:13 – Discovery of carb backloading & early keto 25:16 – Keto and explosive vs. hypertrophy training 26:33 – LDL, lipids & muscle recovery hypothesis 29:40 – Being the odd one out going keto at the gym 30:06 – First ketogenic competition prep (2017) 37:02 – Winning on keto — competitors' reaction 39:12 – Origin story of the Keto Brick 42:50 – 142 bricks sell out in two minutes 44:14 – Launching Keto Savage brand & content creation 54:00 – Business growth & knocking out debt 55:47 – Surviving COVID & buying a grocery store 59:04 – Speaking at KetoCon & coaching beginnings 1:01:11 – Is keto's popularity rising or falling? 1:05:45 – High protein debate for muscle building 1:14:27 – Robert's seven-phase ketogenic protocol 1:20:56 – What reverse dieting is & why it matters 1:22:38 – Getting to 3.9% body fat — risks & rewards 1:28:37 – Cholesterol numbers during extreme leanness 1:32:07 – Inside bodybuilding competitions 1:40:27 – Calories & energy balance debate in keto 1:47:27 – The value of coaching & accountability 1:54:07 – What's next: retreats, apparel & fatherhood 1:56:27 – How having kids shifted Robert's spirituality 2:04:05 – Dave discusses the CLEARLY retraction saga 2:10:18 – Integrity, doing the right thing quietly 2:17:44 – Heartflow partnership & silver linings 2:19:10 – The Cholesterol Code movie launch plans 2:20:43 – Where to find Robert & closing thoughts #FeldmanProtocol #DaveFeldman #RobertSikes #KetoBrick #KetoSavage #KetogenicDiet #NaturalBodybuilding #LowCarbAthletics #MuscleBuilding #ReverseDialing #BodyFat #LDLCholesterol #FatAdaptation #LeanMassHyperresponder #CholesterolCode #KetoPerformance #MetabolicHealth #BodybuildingNutrition

In this episode of The Feldman Protocol, can living with an LDL of 700 for seven years actually leave your arteries plaque-free? Nick Norwitz (MD PhD) makes the case that the conventional cholesterol narrative is far more complicated than mainstream medicine admits, while Dave and Nick also cover the paternalistic medical system, statin side effects in women, Nick's surprising decision to take a cholesterol-lowering drug, and the recent Peter Attia rebuttal to lean mass hypersponder research. --- 🔥 This episode is sponsored by us -- Own Your Labs 👉 `https://ownyourlabs.com/sp/30` Private blood testing services 🩸Over 300 blood tests 💰Extremely affordable ❤️ We love our customers (Yes, we are literally funding the entire podcast from our own company -- so if you want to show your support, keep getting your private blood testing through our service. Thank you! 🙏) --- 🔗 CONNECT WITH DAVE FELDMAN: Main Channel: `https://youtube.com/@realDaveFeldman` X/Twitter: `https://x.com/realDaveFeldman` Instagram: `https://instagram.com/realDaveFeldman` Website: `https://thefeldmanprotocol.com` --- ⏱ Chapters 3:03 – Who is Nick Norwitz? 3:51 – Leaving medicine's conventional path 5:52 – The calling Dave never felt 8:23 – Science communication as medicine's future 10:30 – Empowering patients with information 11:24 – Statins lower GLP-1: the hidden data 13:10 – Death knell of paternalistic medicine 16:19 – Dave's origin: The Feldman Protocol 18:31 – Why "we don't know" comforts patients 21:43 – Nick's illness, misdiagnosis & obsession 24:04 – The podcast origin story & echo disaster 28:41 – Cholesterol Code film blowing up 31:19 – Balancing science and accessibility in film 36:06 – Peter Attia's rebuttal to LMHR research 38:18 – Who's willing to have an open conversation? 41:01 – Causality vs. importance in lipid science 44:17 – Over-medicating metabolically healthy people 47:01 – Statins harm women more: the X chromosome mechanism 50:45 – The nocebo effect as gaslighting 55:03 – Dave's blinded crossover statin experiment 57:04 – Plot twist: Nick is taking a cholesterol drug 59:05 – Ezetimibe and Alzheimer's disease 1:02:01 – Plot twist 2: why Nick chose ezetimibe 1:04:00 – Plot twist 3: the 7-year coronary CT angiography 1:08:19 – Nick's CAD score at year 2 & family risk 1:14:10 – Clinical experience vs. contending with data 1:23:33 – Is Nick anti-statin? Dave presses hard 1:27:34 – Bempedoic acid & PPAR alpha activation 1:32:39 – Peter Attia's article vs. the LMHR team 1:36:24 – How to find Nick Norwitz everywhere --- #FeldmanProtocol #DaveFeldman #NickNorwitz #LDLCholesterol #LeanMassHypersponder #CholesterolCode #StatinSideEffects #Ezetimibe #HeartHealth #LipidResearch #MetabolicHealth #Atherosclerosis #PatientEmpowerment #ScienceCommunication #Bempedoicacid #AlzheimersResearch #CardiovascularHealth #LowCarb #KetogenicDiet