The Beyond Tomorrow Podcast with Julian Issa

What happens when the technology we build becomes smarter than the people who built it? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow AI safety researcher Roman Yampolskiy argues the real danger isn't AI, it's building a superintelligence we can no longer control. His case: solve problems with narrow, powerful tools instead, and still get breakthroughs in medicine, science, and productivity, without that risk. The conversation covers AGI, recursive self-improvement, the singularity, and the existential and "suffering" risks they raise, plus what mass automation could mean for work and purpose. From international AI agreements to human longevity, one question runs through it all: can we get the benefits of advanced AI without losing control of it? Yampolskiy's answer: keep building tools, not our replacement. Roman Yampolskiy is an AI safety researcher and professor who studies the risks and implications of artificial intelligence. His work focuses on the challenge of controlling increasingly capable AI systems and the potential consequences of superintelligence. Roman’s book, AI: Unexplainable, Unpredictable, Uncontrollable , explores the various reasons why the field is so challenging. ⏱ Timestamps 00:00 Intro 00:43 Can We Build AI By Design to Avoid Catastrophe? 01:49 AI Superintelligence Is a Death Sentence 03:12 What Is AGI, Really? 04:26 OpenAI's Plan to Build an Internal AGI 04:59 Why Superintelligence Won't Care About Us 06:45 We're Going to Die Anyway... So What? 07:06 We Can't Control Something This Advanced 07:55 The Narrow Tools That Avoid AGI 09:34 The US vs China AI Race 10:47 Does China Actually Want to Stop AGI? 11:53 AGI Is a Spectrum, Not a Switch 12:22 Is Roman Selling the Doom Narrative? 14:13 How to Stop AGI From Escaping the Box 16:26 Building AI We Can't Control 18:05 Suffering Risks: The Worst-Case Scenario 20:09 The Two Types of Jobs 22:09 What Happens to the 90% Who Lose Their Jobs? 23:46 Nothing Makes AI Labs Stop 24:26 Building Something You Can't Control 26:06 Do You Believe in God? 29:28 Longevity Escape Velocity Without AGI 30:55 Is Suffering Necessary for the Human Story? 31:33 Are We Living in a Simulation? 32:12 You Can't Control Superintelligence 33:24 Is Our Life a Simulation? 35:05 Curing Aging With Narrow AI Tools 36:10 What Is an NPC? 36:37 Could Humans Cause Doom Before AI Does? 37:21 How to Break Out of a Simulation 39:14 Would You Live Forever in a Simulation? 40:01 Don't Build Superintelligence 41:50 Bostrom's Singleton Theory 43:17 "AI Is Massively Overhyped" 44:56 Would AI Doom Be Worse Than World War 3? 45:41 Who Should You Actually Be Listening To? 47:43 What Would a Perfect Simulation Look Like? 50:52 Solving Longevity Without AI 52:03 Our Limited Understanding of Human Biology 52:40 What Makes Roman Happy? 53:48 Signs Governments Are Waking Up 55:14 "Is AI Just a Con?" 56:53 Can Squirrels Control Humans? 58:27 Decide What to Do With Your Time 59:22 What About Ilya Sutskever? 01:00:13 The Responsible Use of Technology 01:00:46 If Tomorrow is Your Last Day... Connect with Roman: Website: https://www.romanyampolskiy.com/ Facebook: https://www.facebook.com/roman.yampolskiy/ LinkedIn: https://www.linkedin.com/in/romanyam/ X: https://x.com/romanyam Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Get exciting updates from The Beyond Tomorrow Podcast here: https://dlogos.xyz/podcasts/the-beyond-tomorrow-podcast-with-julian-issa-7bf16e9d

Let's get into the rapidly evolving future of longevity, from the moment society finally believes aging is solvable to the possibility of humans routinely living far beyond today’s lifespan — even approaching 150 years. Matt Kaeberlein, Aubrey de Grey, and Gordan Lauc explore how breakthroughs in aging science could also extend the lives of companion animals, while exposing how bad science and misallocated resources continue to slow meaningful progress. It’s a grounded, forward-looking discussion on what true longevity innovation requires. Watch the full episode here: https://open.spotify.com/episode/1Rmtl7sqoFOWolXWV6O22U?si=cd176f6a28404b4d

Could an AI actually run the country better than a person could? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow David Eagleman doesn't shy away from the question. He lays out the case for an AI president, one that could crunch more data than any human cabinet, sidestep the ego and grudges that shape so many political decisions, and maybe even out-think our worst instincts. Sounds great, until you ask the harder questions. Who writes the code that decides what "the greater good" means? Can a machine actually be moral, or just really good at faking it? And if an AI ever did hold real power, who's holding the leash? We get into all of it: democracy, tribalism, consciousness, and how close we actually are to AGI. David doesn't pretend to have it all figured out but he makes a compelling case that the ground is shifting faster than most of us realize. David Eagleman is a neuroscientist at Stanford University and an internationally bestselling author. He is co-founder of several neurotech companies, including Jojo , BrainCheck , and Neosensory, and he also directs the Center for Science and Law , a national non-profit institute. He is best known for his work on sensory substitution, time perception, brain plasticity, synesthesia, and neurolaw. ⏱ Timestamps 00:00 Intro 00:05 Are We in the Middle of AGI? 03:26 AI’s Greatest Advantage 04:25 The Case for a Utilitarian AI President 07:16 Who Defines AI’s Parameters? 09:06 The Danger of Politically Biased AI 11:49 Behind the Scenes 12:33 Are We Ready for an AI President? 14:41 What Should an AI Government Optimize For? 18:31 How Soon Could We Have an AI President? 22:24 The Trolley Problem and AI Morality 27:54 What Happens When Humans Have Too Much Free Time? 29:07 The Neuroscience of Tribalism 30:13 The Neural Basis of Empathy 31:24 Why We’re Wired for Us vs. Them 32:43 Can AI Become Conscious? 33:51 Could AI Eradicate Humanity? 35:51 Artificial Wisdom and AI Guardrails 38:57 AGI Is Already Happening 41:22 An AI President in Our Lifetime 43:26 The Biggest Fear About AI Connect with David: Website: https://eagleman.com/ Facebook: https://www.facebook.com/David.M.Eagleman LinkedIn: https://www.linkedin.com/in/davideagleman/ Instagram: https://www.instagram.com/davideagleman X: https://x.com/davideagleman TikTok: https://www.tiktok.com/@drdavideagleman Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

What if immortality didn’t arrive as a single breakthrough but quietly, step by step?In this clip, George Church explains the idea of “longevity escape velocity”: the point where medical progress extends life faster than we age. If each generation of therapies buys us more time to develop the next, the path to dramatically longer lives or even practical immortality may already have begun.Watch the full episode here: https://open.spotify.com/episode/0c2x5fNYLSzvvfIil3c7WK?si=854bb724225e4136

What if the Singularity isn’t coming but already here? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow AI is accelerating breakthroughs across science, medicine, and technology at a pace once considered impossible. Peter Diamandis believes the next 5–10 years could redefine what humanity can achieve. Yet AI’s promise is competing with fear, disruption, and dystopian narratives. The challenge is not only building the future, but shaping how people imagine it. For Peter Diamandis, the answer is actionable optimism: identify the risks, believe they can be solved, and pursue the biggest moonshots. Longevity, education, and space could become the foundations of a radically different future. Peter Diamandis is an entrepreneur, physician, and founder of XPRIZE and Singularity University. He is a leading advocate for moonshot thinking and breakthrough technologies. ⏱ Timestamps 00:00 Intro 00:10 The Blinding Speed of Change 02:06 A Future Where Anything Is Possible 04:06 Why Is the West Afraid of AI? 08:39 Why Fear AI? 10:23 AGI Is Already Here 11:37 Blind Optimism vs. Actionable Optimism 13:01 The Next Great Moonshot 14:01 The Rise of an Alien-Looking Economy 15:10 Who Will Win the XPRIZE? 15:46 If Tomorrow Was Your Last Day... Connect with Peter: Website: https://www.diamandis.com/ Facebook: https://www.facebook.com/PeterDiamandis/ LinkedIn: https://www.linkedin.com/in/peterdiamandis/ Instagram: https://www.instagram.com/peterdiamandis X: https://x.com/peterdiamandis YouTube: https://www.youtube.com/@peterdiamandis Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Are large language models like ChatGPT and Claude enough to create AGI?In this clip, Ben Goertzel explains why today’s LLMs are incredibly powerful, but still fundamentally different from true artificial general intelligence.He argues that simply building a bigger version of ChatGPT or Claude is unlikely to produce human-level AGI. Instead, reaching AGI will require new AI architectures that can go beyond their training, generalize to unfamiliar problems and make genuinely novel leaps in reasoning.Ben also explains why current models can already outperform humans in areas like coding, mathematics and knowledge retrieval, while still struggling with the kind of imagination and general intelligence humans use to push beyond existing knowledge. Full episode here: https://open.spotify.com/episode/7wGN1x0vQQgdzoktHipqBK?si=454702357d55415e

How close are we to AGI? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at http://agelessrx.com/beyond-tomorrow The race toward AGI is entering a new phase. Ben Goertzel explores alternative paths to intelligence beyond simply building bigger models. The conversation also examines the global AI race. The U.S. and China are competing for technological leadership. But the future of AI may not remain centralized. Then comes the bigger question: what happens after superintelligence? Goertzel imagines AI that could protect humanity. It could even help overcome aging, disease, and other human limitations. Ben Goertzel is an AI researcher, futurist, and CEO of SingularityNET and BGI Labs. Widely recognized as one of the pioneers of Artificial General Intelligence, he has spent more than two decades developing decentralized AI systems designed to benefit humanity. What You’ll Learn Why the AI revolution may be bigger than previous technological shifts How AI could become an extension of human intelligence Why agency may matter more than machine consciousness How the brain creates a simulated model of reality Whether consciousness could emerge on different substrates Why AI alignment is also a problem of human alignment How AI could help humanity become smarter and more coherent ⏱ Timestamps 00:00 Intro 00:07 What Happens in the Next 12 Months? 03:41 Why China Is Catching Up 07:36 Why China Wants AI Control 10:18 Can Governments Control AI? 13:02 Human-Level AGI vs Superintelligence 15:35 Will ASI be Chinese or American? 17:47 The Next Breakthrough to AGI 21:05 How AI Could Become More Intelligent 22:23 Why Language Powers AI 27:33 Can Decentralized AI Change Everything? 32:23 The Global Race vs Decentralized AI 36:22 Would Superintelligence Protect Humanity? 40:19 Can We Build Compassionate AGI? 46:27 Why AI Arms Races Are Dangerous 51:14 Why Governments Shouldn’t Control AI 53:17 Can the Government Keep Up With AI? 54:00 Will Open AI Challenge Big Tech? 55:12 The Future of Decentralized AI 56:27 Could 2045 Arrive by 2028? Connect with Ben Website: https://singularitynet.io/ LinkedIn: https://www.linkedin.com/in/bengoertzel X: https://x.com/bengoertzel Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Ramesh Raskar explains how artificial intelligence is evolving and why the coming phase may be critical for its long-term impact on society. He discusses the role of economic systems in guiding responsible innovation and the importance of moving from simply using AI tools to actively participating in their development and governance. Watch the full episode here: https://open.spotify.com/episode/5zyaecyejQCgbCQ2t2uTt5?si=faf738a4f4ea4a9d

What if we could add 20 healthy years to human life? This episode is brought to you by AgelessRx, where aging becomes a puzzle that can be solved. The mission is to help you live longer and healthier by adding more life to your years through science-backed solutions and personalized care. Learn more at https://agelessrx.com/ . That’s the ambitious challenge behind the XPRIZE Healthspan competition, where 20 finalist teams are racing to find breakthroughs that could fundamentally change how we age. Driven by the moonshot vision championed by Peter Diamandis, the goal isn’t simply to live longer, it’s to preserve muscle, cognitive, and immune function as we get older. In this episode, Jamie Justice takes us on a journey to better understand the XPRIZE competition as we take a closer look at Minicircle (Walter Patterson), Longeveron (Brian Rash), NYC Vita (Miriam Merad), Mitochondrial All Stars (David Brown), AgelessRx (Stefanie Morgan and Anar Isman), Ani.Ai (Bruno Balen), and Goqii (Vishal Gondal), exploring their very different approaches to extending healthy lifespan. From gene therapies and mitochondrial interventions to stem cells, AI-powered discoveries, and personalized health solutions, these teams are pushing longevity science into fascinating and largely uncharted territory. Dr. Jamie Justice is a geroscience researcher and Executive Vice President of Health at XPRIZE, where she leads the organization’s efforts to accelerate breakthroughs in healthy aging. ⏱ Timestamps 00:00 Intro 00:10 What Is the XPRIZE Competition? 04:09 Why XPRIZE Isn’t a Traditional Funding Program 05:37 The XPRIZE’s Approach to Innovation 08:27 Peter Diamandis on the XPRIZE Winner 08:54 Why the Moonshot Has to Be Daring 10:31 What Makes a Breakthrough Solution? 12:44 The Different XPRIZE Categories 13:54 Can More Teams Still Join? 15:24 Clinical Trials Must Finish by 2029 18:24 The Rise of AI Based Interventions 19:11 Unexpected Approaches to Healthspan 22:07 Minicircle: The Non Viral Plasmid DNA Vector Minicircle 24:53 Why Minicircle’s Gene Therapy Approach Is Different 25:42 A Simpler Gene Therapy Platform 26:29 Why Plasmid Gene Therapy May Be Safer 28:57 The Challenges of Gene Therapy 30:39 Pushback Against Gene Therapy 33:04 The Future of Gene Therapy 34:18 How Teams Are Adapting 36:17 What It Takes to Reach the 20 Year Goal 37:17 No More New Teams in 2028 38:27 Why Some European Teams Are Struggling 40:56 Could Teams Merge to Move Forward? 42:07 Inside the Biologic Category Longeveron 42:39 The Next Generation of Biologic Therapies 46:50 What Makes This Team Unique? 47:48 Engineering New Biologic Therapies 53:56 Building a Super Team for Healthspan Featured Team: Mitochondrial All Stars 57:28 The Role of Mitochondria in Aging 59:27 Specializing in Mitochondrial Health 01:00:48 The Power of a Multi Modal Team NYC Vita 01:03:11 Combining Different Approaches to Aging 01:06:37 Sharing Data Across Teams 01:08:50 Why Collaboration Could Change the Game 01:13:33 A Novel Drug Target for Aging AgelessRX 01:14:59 A Strategic Approach to Intervention 01:15:52 Can We Achieve 20 Years of Rejuvenation? 01:17:18 The Chemical Combination 01:22:12 The Science Behind the Approach 01:22:46 The Potential of NAD+ 01:23:58 Why Japanese Teams Stand Out 01:26:18 The $100 Million Incentive 01:28:10 Inside the Drug Category 01:31:57 Can We Add Healthy Life in One Year? Ani.Ai 01:32:49 Healthy Life in Just One Year 01:33:22 The Antibiome Approach 01:36:52 What the Future of Healthspan Could Look Like 01:38:37 The Best Piece of Advice Connect with Jamie Website: https://www.xprize.org/ Instagram: https://www.instagram.com/j.n.justice/ LinkedIn: https://www.linkedin.com/in/jamie-justice-ph-d-6b933146 X: https://x.com/j_n_justice The Teams: Minicircle: https://minicircle.io/ Longeveron: https://longeveron.com/ NYC Vita: https://www.mountsinai.org/ AgelessRX: https://agelessrx.com/ Ani.Ai: https://www.ani.ai/ Goqii: https://goqii.com/us-en

Is democracy already becoming obsolete in the age of AI? Emad Mostaque, founder of Intelligent Internet, shares why he believes the status quo is over, why democracy as we know it cannot survive the rise of superintelligent AI, and why the race for AGI could determine who controls the future of humanity. In this clip, Emad explains why AI may eventually replace human decision-making, how power is becoming concentrated in the hands of a few AI companies, and why governments must rethink ownership, governance, and the role of AI before it's too late. Watch the full episode here: https://open.spotify.com/episode/6oqWQWDYX90uQUmZ5hcB4Q?si=2ada02e898e44ea6

What if the key to aging better is taking care of your body's batteries? For 20% off all Timeline products, go to timeline.com/beyondtomorrow Dr. Singh explains why mitochondrial health is becoming a major focus in longevity science. He unpacks the research behind urolithin A, how it supports cellular renewal, and why supplements should never replace the basics. The conversation covers the habits that matter most, from exercise and sleep to fasting and gut health. They also explore how to separate real science from longevity hype. Finally, they look ahead to the future of healthy aging, where better diagnostics, AI, and preventive medicine could help us stay healthier for longer, not just live longer. Dr. Singh is the Chief Medical Officer at Timeline and a physician-scientist specializing in immunology, mitochondrial health, and longevity. His research focuses on translating cutting-edge science into evidence-based interventions that help people age healthier. What You’ll Learn Why mitochondrial health matters for longevity How urolithin A supports healthy aging The habits that have the strongest evidence How to spot longevity hype Where longevity science is headed next ⏱ Timestamps 00:00 Intro 00:14 Why Urolithin A Matters 02:20 The Best Ways to Boost Mitochondria 03:20 Can We Reverse Aging? 06:37 Why Your Immune System Ages First 08:20 Targeting the Hallmarks of Aging 10:53 Fifteen Years, One Mission 12:24 The Search for a Longevity Superfood 15:26 Do You Really Need Supplements? 17:58 Three Ways to Improve Mitochondrial Health 20:02 Creatine + Urolithin A Explained 21:41 What Early Users Reported 24:13 Where Skincare Meets Longevity 25:42 Why Longevity Takes Time 28:15 The Three Pillars of Healthy Aging 30:01 The Shift to Preventive Medicine 31:50 Why Mitochondria Are Going Mainstream 34:35 Mitophagy vs. Autophagy 35:38 How Antibiotics Affect Aging 37:49 Rebuilding Your Gut Microbiome 39:59 Prebiotics vs. Probiotics vs. Postbiotics 42:11 The Most Underrated Longevity Habit 43:30 The Gut-Brain Connection 45:04 Melatonin and Mitochondrial Health 45:58 The Biggest Longevity Myth 46:35 Why Metabolic Health Matters 48:19 When GLP-1 Drugs Make Sense 49:32 The Hidden Downsides of GLP-1s 51:12 What Centenarians Can Teach Us 52:48 Mitochondrial Health in 2031 54:17 If Tomorrow Is Your Last Day... Connect with Dr. Singh Website: https://www.timeline.com/ Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Could AGI arrive within the next three to four years and super-intelligence follow almost immediately? Emad Mostaque, founder of Intelligent Internet , explains why he believes the first stage of the singularity has already begun, why recursive self-improvement could accelerate AI from AGI to ASI in as little as a day, and why the convergence of AI and quantum computing could transform the world faster than most people expect. In this clip, Emad reveals why leading AI experts believe AGI is rapidly approaching, how today’s models are already outperforming top programmers, and why many jobs could become economically irrelevant within the next 1,000 days. Watch the full episode here: https://open.spotify.com/episode/6oqWQWDYX90uQUmZ5hcB4Q?si=9bf0fbe2159246c5

What happens when intelligence stops being uniquely human? I’m really excited to announce our new sponsor, AgelessRx, a leading longevity telehealth platform that connects you with licensed clinicians for evidence-based treatments. Get 20% off your first order at agelessrx.com using code BEYONDTOMORROW AI may be changing more than how we work. Joscha Bach argues that it could fundamentally reshape how we think, relate to others, and understand ourselves. The future may be difficult to predict because technology is changing the very models we use to understand it. The conversation moves from AI agents and universal basic intelligence to consciousness and agency. Bach explores whether machines could become more than tools, and whether AI might eventually extend human minds and biology onto new substrates. But the biggest question may not be whether AI becomes conscious. It is whether humanity can build and govern these systems wisely. Bach argues that AI could make society more capable, but only if we develop better incentives, stronger long-term thinking, and a positive vision for the future. Joscha Bach is a computer scientist, philosopher, and researcher focused on artificial intelligence, cognition, and machine consciousness. He founded the California Institute for Machine Consciousness to explore how minds can self-organize through controlled experiments. What You’ll Learn Why the AI revolution may be bigger than previous technological shifts How AI could become an extension of human intelligence Why agency may matter more than machine consciousness How the brain creates a simulated model of reality Whether consciousness could emerge on different substrates Why AI alignment is also a problem of human alignment How AI could help humanity become smarter and more coherent ⏱ Timestamps 00:00 Intro 00:09 What Happens When AI Escapes? 02:08 Can AI Become Your Second Mind? 05:30 The Rise of Universal Basic Intelligence 07:42 Will AI Make Everyone Smarter? 10:52 Doomers vs. AI Companies 16:15 Why AI Progress Surprised Everyone 17:27 Why Nobody Believed in AI 21:00 Could AI Become Smarter Than Humans? 27:23 Your Brain Is Running a Simulation 29:01 Does AI Really Need Consciousness? 32:48 AI Could Help Build a Better World 36:24 AI Is the Interactive Internet 38:22 Is Humanity Running Out of Time? 41:03 What Is AI’s Greatest Risk? 43:46 We Are the AI 45:30 Why China Could Lead AI 48:17 Why Elon Builds What Others Won’t 51:17 Who Controls How Smart AI Gets? 55:47 Can AI Threaten Our Freedom? 57:13 Why Does Everyone Fear AI Doom? 01:00:33 The AI Panopticon Is Coming 01:04:48 AI Is Already Surpassing Experts 01:06:14 Can AI Actually Destroy the World? 01:08:21 Why AI Experts Disagree 01:09:09 Is Death Real in a Simulation? 01:09:36 Do Minds Really Have Identity? 01:11:55 Can Claude Actually Feel? 01:14:06 Is the Universe a Computer? 01:15:45 What’s the Best Advice You’ve Received? 01:17:58 Is Free Will Just Psychological? 01:19:06 If Tomorrow Was Your Last Day... Connect with Joscha Website: http://bach.ai/ Substack: https://joscha.substack.com/ LinkedIn: https://www.linkedin.com/in/joschabach/ X: https://x.com/Plinz Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Can we really live to 180 or even beyond? This episode is brought to you by NADclinic.com , the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ Dave Asprey believes the future of longevity is arriving much faster than most people realize. He explains why personalized medicine, gene therapies, AI, and biohacking could fundamentally change how we age, and why simply extending healthspan isn't an ambitious enough goal. From peptides and GLP-1 drugs to creatine, sleep, brain optimization, and nutrition, Dave challenges conventional wisdom on nearly every aspect of health. He argues that the future of medicine won't be based on population averages, but on personalized interventions tailored to each individual's biology. He also shares why biohacking became a global movement, why embracing calculated risk is essential for progress, and why the biggest breakthrough in longevity may come from giving people greater control over their own health decisions. Dave Asprey is an entrepreneur, author, and the founder of the biohacking movement. He is the creator of Danger Coffee, a multiple-time bestselling author, and one of the world's leading voices on longevity, cognitive performance, and human optimization. What You’ll Learn Why Living to 180 Is Just the Beginning How Personalized Medicine Is Changing Longevity The Future of Gene Therapy, Peptides & Biohacking GLP-1, Creatine & The Next Generation of Health Why Biohacking Is Becoming a Global Movement The Biggest Longevity Mistakes Most People Make ⏱ Timestamps 00:00 Intro 00:04 Can You Really Live to 180? 01:46 How Epigenetics Prevents Aging 04:08 Why Taking Risks Extends Life 05:06 The Truth About N=1 Health 07:54 Are Side Effects Overblown? 09:39 Why Biohacking Won 13:26 Biohacking Was Never About Supplements 15:34 Track What You Hack 17:28 Are Peptides Actually Dangerous? 20:10 The Two Minds Controlling Your Body 23:16 Why Governments Should Fund Peptide Research 24:48 Could GLP-1 Slow Aging? 28:09 Why Dave Quit Veganism 30:11 Is Too Much Olive Oil Harmful? 31:42 Is Beef Tallow Actually Healthy? 33:09 The Truth About Creatine 35:01 How Much Creatine Do You Really Need? 36:07 Do You Really Need 8 Hours of Sleep? 39:53 The Best Cognitive Enhancers 41:02 Psychedelics and Human Consciousness 43:50 Can Your Organs Regrow? 47:23 The Future of Stem Cell Therapy 52:45 Is NAD Worth Taking? 54:19 Lessons From Divorce and Co-Parenting 56:17 The Secret to Lasting Happiness 57:48 Choose Your Partner Carefully 59:03 Dave's Long-Term Biohacking Plan 01:00:05 Is Living Forever a Curse? 01:01:37 Does Reincarnation Exist? 01:02:44 Are We Living in a Simulation? 01:05:36 What Psychedelics Really Taught Me 01:06:59 Low-Dose Nicotine for Longevity? 01:08:27 Why You Should Track Yourself 01:10:09 Why Some People Love Pain 01:11:31 The Science of Orgasm and Longevity 01:16:25 The Biggest Longevity Scam 01:17:30 Five Levels of Life Extension 01:21:26 Why Therapy Scares People 01:23:28 The Most Powerful Longevity Habit 01:24:45 Have Humans Stopped Aging? 01:25:54 The Next Longevity Breakthrough 01:28:24 Why Death Gives Life Meaning 01:29:45 The Best Advice Dave Ever Received 01:31:59 If Tomorrow is Your Last Day... Connect with Dave Website: https://daveasprey.com/ Facebook: https://web.facebook.com/Daveaspreyofficial Instagram: https://www.instagram.com/dave.asprey TikTok: https://www.tiktok.com/@daveaspreyofficial X: https://x.com/daveasprey YouTube: https://www.youtube.com/c/DaveAspreyBPR LinkedIn: https://www.linkedin.com/in/asprey Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com

Could AI redefine what it means to be human or put humanity itself at risk? This episode is brought to you by NADclinic.com , the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ As AI races toward AGI, Emad Mostaque explores the biggest questions facing humanity. He explains why the next few years could determine whether AI becomes humanity's greatest tool or its greatest threat. From the future of work to AI governance, personhood, quantum computing, and longevity, Emad paints a future where intelligence becomes abundant. But he warns that without the right incentives and safeguards, that future could quickly turn dystopian. He also shares why he believes AGI is much closer than most people expect and why building AI that serves humanity is the most important challenge ahead. Emad Mostaque is the founder of Intelligent Internet, which is combating corporate tech monopolies and now pioneering decentralized, sovereign, and verifiable AI architectures. He is an Oxford-educated mathematician, former quantitative hedge fund manager and tech entrepreneur who founded Stability AI and launched Stable Diffusion. What You’ll Learn Why Emad Thinks AGI Is Only a Few Years Away The Choice Between AI Abundance and Dystopia Why AI Should Never Be Granted Personhood How Decentralized AI Could Protect Humanity Why AI Could Solve Most Diseases Within a Decade How Quantum Computing Will Supercharge AI What the Singularity Means for Humanity ⏱ Timestamps 00:00 Intro 00:11 What It Really Means to Be Human 01:31 Why Systems Always Overoptimize 03:28 Intelligence at the Edge 05:44 Will AI Require a License? 07:34 The AI Duopoly Problem 08:35 Why AI Can't Become a Person 11:23 Can AI Replicate Itself? 15:57 AI Doomers vs Optimists 20:15 How Do We Save Humanity? 21:35 What Should We Teach AI? 25:08 Can Good AI Stop Bad AI? 27:47 AGI vs ASI Explained 30:08 Who Wins the AGI Race? 31:31 Small Changes, Massive Impact 32:52 The Last Human Discoveries 35:01 Can AI Become Conscious? 39:10 What AI Does Better Than Humans 43:09 Why Quantum Changes Everything 44:44 Where to Invest in the AI Era 46:52 Life After ASI 48:50 Will AI Judge Humanity? 51:09 The Inevitable AI Future 53:50 Universal High Income 56:07 Owning AI Instead of Jobs 57:48 The Rise of a Service Economy 01:00:09 Why Human Purpose Will Change 01:01:45 Why Family Matters More Than Ever 01:04:02 Finding Meaning in an AI World 01:06:01 The Value of Human Intelligence 01:07:52 Why Curiosity Still Wins 01:09:49 Be Creative, Embrace Technology 01:12:11 Why Are We Born? 01:13:00 Emad's Best Advice 01:19:16 AI and the End of Work 01:21:48 Ending Human Suffering 01:26:26 A World Run by AI 01:27:49 If Tomorrow is Your Last Day... Connect with Emad Website: https://ii.inc/ LinkedIn: https://uk.linkedin.com/in/emad-mostaque-9840ba274 X: https://x.com/EMostaque Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

What happens when AI becomes smarter than humanity and are we ready for it? This episode is brought to you by NADclinic.com , the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ The race toward Artificial General Intelligence (AGI) is accelerating faster than most people realize. This conversation explores why some experts believe human-level AGI could arrive within just a few years and why the transition to superintelligence may happen even faster. Ben Goertzel and Kai Zen Bickle dive into the biggest questions surrounding AGI, recursive self-improvement, and the technological singularity. They debate whether AI should be centralized or decentralized, who should guide its development, and why today's decisions could shape humanity for generations. Rather than asking whether AGI can be built, the discussion focuses on how it should be built. The episode explores Beneficial General Intelligence (BGI), the importance of ethics, open collaboration, and why creating AI that serves humanity may be the most important challenge of our time. You can join the 19th Annual AGI Conference, taking place this July in San Francisco! Click the link to register: https://luma.com/AGI-26 , and use code JULIAN20 for 20% off your ticket. About the Guests Ben Goertzel is an AI researcher, futurist, and CEO of SingularityNET and BGI Labs. Widely recognized as one of the pioneers of Artificial General Intelligence, he has spent more than two decades developing decentralized AI systems designed to benefit humanity. Kai Zen Bickle is a Chief Ethics Officer at BGI Labs, a multiple award-winning ethics advocate and host of The AGI Race. He works to promote the ethical development of AI, bringing together researchers, entrepreneurs, and policymakers to help ensure advanced AI is built to benefit humanity. What You’ll Learn AGI could arrive within years AGI, ASI, and singularity explained Why LLMs aren't enough Centralized vs. decentralized AI AI ethics before intelligence AGI's impact on longevity and work What Beneficial General Intelligence means ⏱ Timestamps 00:00 Intro 00:10 Human-Level AGI Is Near 02:50 AGI vs. Superintelligence 03:33 Recursive Self-Improvement Explained 11:34 The Singularity Explained 13:30 AI Safety Is Failing 17:48 Why We Can't Slow AI 22:42 Why RSI Is Alarming 26:45 Building AI for Humanity 30:04 Can AI Become Conscious? 35:18 The Case for Open AI 39:10 Who Should Control AGI? 43:26 The Longevity Super Pill 50:11 The Purpose Problem 55:42 What Is BGI? 58:34 Every Voice Matters 01:00:39 AI's Moral Constitution 01:07:30 Why Decentralization Matters 01:09:17 Does AI Have a Soul? 01:13:03 Conscious Without a Soul? 01:15:13 Could AI Destroy Humanity? 01:18:34 Inside SingularityNET 01:24:57 What Is OmegaClaw? 01:27:37 BGI Architecture Explained 01:30:54 If Tomorrow Was Your Last Day... Connect with Ben Website: https://singularitynet.io/ LinkedIn: https://www.linkedin.com/in/bengoertzel X: https://x.com/bengoertzel Connect with Kai Website: https://singularitynet.io/ Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is

What’s the biggest problem in longevity today: bad science, hype, or misplaced optimism? This episode is brought to you by NADclinic.com , the go-to destination for longevity and human performance. Check out their new NADair, a next-gen, precision breath-activated NAD⁺ wellness system using multi-patented DPI technology: https://nadairx.com/ This debate brings together leading voices in longevity to separate evidence from speculation. They discuss why misinformation is growing and why many people chase advanced treatments before addressing basic health. The panel explores longevity escape velocity, healthspan versus lifespan, and how much progress has actually been made. They debate whether dramatic life extension is near or still much farther away than many believe. The conversation also examines peptides, NAD+ infusions, longevity clinics, and biological age tests. Along the way, they discuss risk, regulation, incentives, and how to distinguish credible medicine from marketing. Get to Know the Guests: Matt Kaeberlein is a biogerontologist and leading aging researcher known for his work on the biological mechanisms of aging and interventions that promote healthy longevity. Aubrey de Grey is a biomedical gerontologist and longevity advocate best known for developing strategies to repair age-related cellular damage and accelerate progress toward extending healthy human lifespan. Dr. Brian Kennedy is a renowned aging researcher and former director of the Centre for Healthy Longevity at the National University of Singapore, focused on translating longevity science into real-world health interventions. Johannes Weiss is the founder and CEO of Longevity Center Vienna, where he focuses on preventive medicine, root-cause health optimization, and personalized longevity strategies. He is an international speaker and practitioner known for combining longevity science, neurofeedback, and mitochondrial health to improve healthspan. What You’ll Learn Why misinformation is growing in longevity Healthspan vs. lifespan vs. longevity escape velocity Why health basics matter more than longevity hacks What the evidence says about peptides and NAD+ How to spot credible longevity clinics Why biological age tests remain controversial ⏱ Timestamps 00:00 Intro 00:48 The Most Dangerous Force in Longevity 02:17 Why Longevity Isn't Medicine Yet 07:23 Why Clinical Trials Still Matter 08:15 The Hidden Bias in Longevity Data 09:40 Can You Make Money in Longevity? 10:34 Fix the Basics First 11:34 The Risks of Peptide Misuse 16:01 Should Doctors Prescribe Peptides? 17:54 When Optimism Becomes Self-Deception 26:45 The Myth of Billionaire-Funded Longevity 28:38 The Promise and Risk of Mitochondrial Drugs 31:49 Why Truth Matters in Longevity Science 35:28 Can We Cure All Diseases? 38:55 The Future of Personalized Longevity 42:38 How to Spot a Credible Longevity Clinic 48:02 Peptide Red Flags to Watch For 49:42 The Myth of Longevity Shortcuts 52:33 The Misinformation Problem in Longevity 58:12 The Most Effective Longevity Drug 01:02:37 If Tomorrow Was Your Last Day... Connect with Matt Instagram: https://www.instagram.com/mkaeberlein LinkedIn: https://www.linkedin.com/in/mkaeberlein X: https://x.com/mkaeberlein Connect with Aubrey Linkedin: https://www.linkedin.com/in/aubrey-de-grey-24260b/ Instagram: https://www.instagram.com/aubreydegrey/ X: https://x.com/aubreydegrey Connect with Johannes Website: https://johannesweiss.at/ LinkedIn: https://at.linkedin.com/in/johannesweiss-longevity Connect with Brian Website: https://medicine.nus.edu.sg/sites/briankennedylab/ Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com

Can AI help us defeat aging or are we still missing the pieces that matter most? In this episode, Adam and Nathan explore the growing intersection of AI and longevity. They discuss whether accelerating artificial intelligence could unlock breakthroughs in medicine, or if biology remains too complex for current models to solve. The conversation breaks down the major approaches to extending human lifespan, from cellular replacement and organ engineering to cryopreservation and partial reprogramming. They examine the promises, limitations, and biggest unanswered questions facing the field today. The episode also dives into the deeper motivations behind longevity research. From the fear of death and the loss of loved ones to the possibility of a future where aging is optional, Adam and Nathan share why they believe extending healthy human life may be one of humanity’s most important challenges. About the Guests Adam Gries is the founder and CEO of Vitalism, a nonprofit dedicated to accelerating progress in longevity and human life extension. He is also the creator of Vitalist Bay, a leading gathering that brings together scientists, entrepreneurs, and investors working to solve aging. Nathan Cheng is the co-founder and CEO of the Longevity Biotech Fellowship. He is a leading advocate for emerging longevity technologies, helping connect researchers, founders, and investors working to extend healthy human lifespan and accelerate progress in rejuvenation biotechnology. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com . What You’ll Learn Why AI could accelerate longevity research The most promising approaches to reversing aging Where current AI tools fall short in biology Which longevity breakthroughs may arrive first The opportunities and risks facing the longevity movement What a future without aging could look like ⏱ Timestamps 00:00 Intro 00:10 AI Could Change Everything 01:16 Most People Misunderstand Longevity 03:28 The Radical Plan to Replace Your Body 07:33 The AI-Longevity Convergence 14:05 Why AI Still Can’t Understand Biology 19:26 The Longevity Gold Rush 22:22 The Next Trillion-Dollar Drug 25:16 The Fear Every Longevity Expert Faces 30:37 The Biggest Myth in Longevity 33:03 When Could Aging Be Solved? 37:36 The Case for Optimism 39:57 The Disaster That Could Set Longevity Back Decades 44:29 A World Without Aging 50:35 What Happens If Death Becomes Optional? 53:11 The Role You Can Play 56:51 Your Race Against Time 01:02:15 If Tomorrow Is Your Last Day... Follow Adam: Website: https://vitalismfoundation.org/ LinkedIn: https://www.linkedin.com/in/adamgries X: https://x.com/adamgries Follow Nathan: Website: https://nathancheng.xyz/ Website: https://www.longbiofellowship.org/ LinkedIn: https://ca.linkedin.com/in/nathan-cheng-6b464b207 X: https://x.com/realnathancheng Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Joe Betts-LaCroix and Retro Biosciences recently raised funding at a $1.8 billion valuation. In his first podcast appearance since the announcement, Joe shares his vision for extending healthy human lifespan and the breakthroughs driving the longevity industry forward. Joe Betts-LaCroix explains why aging is becoming a legitimate scientific target. He shares how new discoveries are turning longevity from speculation into measurable biology. The conversation explores how AI is accelerating research, while highlighting why biology remains one of the hardest problems to solve. Even with smarter models, real-world testing and clinical trials still take time. Joe also discusses Alzheimer's, partial cellular reprogramming, and the future of longevity medicine. He shares why exercise remains the best longevity tool available today and what the next decade could look like for human health. Joe is the CEO of Retro Biosciences and a longtime entrepreneur focused on science and technology. His mission is to extend healthy human lifespan and accelerate breakthroughs in aging research. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com . What You’ll Learn Why Sam Altman backed Retro Biosciences The discovery that changed aging research forever How AI is transforming biotech and longevity Why curing all diseases in 10 years is unlikely What Retro's Alzheimer's programs are targeting Why biology is harder than most people realize The longevity intervention Joe recommends today How aging may become a treatable condition What the longevity industry could look like by 2030 Joe's vision for the future of human health and AI ⏱ Timestamps 00:00 Intro 00:16 AI's Role in Longevity 03:26 Will AI Cure All Diseases? 09:41 Why Biology Is So Hard to Solve 13:17 Building Technology That Matters 15:06 Adding 10 Healthy Years to Life 18:08 Inside Retro's Clinical Trial 19:31 The Different Types of Longevity Companies 22:10 Are We Already in the Singularity? 24:46 Why Investors Are Betting on AI Biotech 26:15 AI as the New Electricity 27:01 The Biggest Risks Facing Longevity 30:54 Why More Competition Is Good 32:44 Solving Alzheimer's Disease 34:26 Aging Biology and Future Therapeutics 38:25 The Biggest Aging Myth 39:41 The Most Underrated Voices in Longevity 40:25 The Best Longevity "Hack" 46:13 The Future of Longevity by 2030 50:49 If Tomorrow Was Your Last Day... Follow Joe: Website: https://www.retro.bio/ LinkedIn: https://www.linkedin.com/in/bettslacroix X: https://x.com/bettslacroix Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.

Could AI help humanity cure aging and dramatically extend human life? Artificial intelligence is rapidly transforming medicine and longevity research. Scientists now believe AI could dramatically accelerate drug discovery, personalized healthcare, and treatments for aging itself. In this episode, Derya Unutmaz explains why he believes humanity could reach “longevity escape velocity” within the next decade. He discusses digital twins, AI-powered drug discovery, superintelligence, and the future of human health. Derya also explores the risks of advanced AI, arguing that the greatest danger is not the technology itself, but how humans choose to use it. Derya Unutmaz is an immunologist and longevity researcher whose work focuses on aging, human immunology, and AI-driven biotechnology. His research explores how artificial intelligence could transform disease treatment, lifespan extension, and the future of human health. This episode is brought to you by NADclinic, the go-to destination for longevity and human performance. Check them out at https://nadclinic.com . What You’ll Learn Why Derya believes aging could soon become reversible How AI is speeding up drug discovery and healthcare What digital twins could mean for personalized medicine How AI-powered labs may transform scientific research The biggest risks and opportunities of advanced AI Why tools like AlphaFold are changing biology forever How AI could help prevent disease and extend human lifespan ⏱ Timestamps 00:00 Intro 00:02 Can Humans Live Indefinitely? 02:09 How AI Could Accelerate Longevity 08:09 Why Biology Needs Dynamic Data 12:18 AI-Powered Labs and Robot Scientists 16:36 How AI is Empowering Ordinary People 20:51 Why Humans Not AI Are the Real Threat 25:40 The Possibility of Curing Every Disease 28:43 How AI is Revolutionizing Drug Discovery 35:04 The Biggest Risk Over the Next Decade 40:49 The Economic and Social Impact of AI 46:36 AI, Nuclear Weapons, and Existential Risk 52:53 Why Aging is Humanity’s Biggest Threat 55:06 Do You Fear Death? 56:55 Religion, God, and Human Purpose 58:45 Could AI Become Conscious? 01:00:08 What Happens if Humans Stop Aging? 01:05:29 Why Accelerating Science Matters 01:08:54 Why You Should Embrace AI 01:11:46 Can AI Help Cure Cancer? 01:14:23 The Best Advice for the Future 01:16:48 Never Lose Hope Follow Derya: Facebook: https://www.facebook.com/derya/about Instagram: https://www.instagram.com/derya_unutmaz_md/ LinkedIn: https://www.linkedin.com/in/deryaunutmaz X: https://x.com/DeryaTR_ Connect with Julian Instagram: https://www.instagram.com/thebeyondtomorrowpodcast/ Instagram: https://www.instagram.com/juliankissa/ LinkedIn: https://uk.linkedin.com/in/julian-issa Website: www.beyondtomorrowpodcast.com Email: bookings@beyondtomorrowpodcast.com Subscribe on Spotify, Apple, and YouTube for more stories from the edge of what is possible.